I’m by no means an expert on this, but I have used both Bazzite and Fedora workstation as my exclusive operating systems.

What I would say is that they’re both perfectly adequate for the tasks you described.

Personally, I’d say unless you prefer things handed to you, choose Fedora. I don’t have a problem with flatpacks, but I missed being able to easily use dnf. At the end of the day, though, there are ways around everything; you can still get what you need done on Bazzite.

In terms of kernel tweaks, etc. I barely noticed any difference in performance between the 2. Keep in mind that this was a relatively modern pc so performance wasn’t really an issue that I was looking out for.

Overall though, you’ll be fine whatever you choose. I also had to use MS office for work and it’s pretty much the one thing you can’t get working on Linux. You’ll have to explore your options for that, I ended moving back to a Mac because of Ableton live :(

If you want specific, I found this: https://journals.sagepub.com/doi/10.1177/1354856520938602

It’s frustrating, considering that ableton’s push runs on Linux, but I never had a satisfactory, or comparable experience running it on a Linux desktop. To be honest, this was the dealbreaker that kept me using a Mac.